Alzheimer's Disease Archive

Ask the doctor

Q. With the holidays coming, I may be tempted to drink more than usual — maybe enough to have a hangover the next morning. I'm wondering if a hangover could actually damage my brain.

A. There have been a few scientific studies of that question. Recently, a team of scientists examined those existing studies, involving over 1,100 people, and came to some tentative conclusions, published online August 25 by the journal Addiction.

Ask the doctor

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Q. Is there something stronger than aspirin I can take for peripheral artery disease in my legs?

A. People with peripheral artery disease (PAD) in the legs have blockages (plaques of atherosclerosis) in the arteries that impair the flow of blood. Based on large scientific studies involving over 5,000 people with PAD, authorities recommend taking a daily aspirin tablet. For people with PAD, smoking cessation, regular exercise, and often other medicines such as statins, can help prevent further plaque buildup and decrease symptoms.

The number of people with dementia is expected to climb to 50 million in the coming decades, but understanding the connection between vascular health and cognitive health allows people the opportunity to adopt heart-healthy habits that can also reduce their risk of dementia.

Sometimes attention deficit hyperactivity disorder is behind issues with memory and task completion.

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You may be concerned about your memory if you notice that you're struggling to keep track of items you use each day, getting sidetracked when doing chores and other tasks, and tuning out during conversations. But it could be that you have attention deficit hyperactivity disorder (ADHD), a brain wiring difference once recognized only in children. In adults, ADHD often produces problems with memory and attention rather than hyperactivity.

"Two to three percent of people in their 60s or older have traits of ADHD that are impairing," says Dr. Craig Surman, a neuropsychiatrist and ADHD researcher at Harvard-affiliated Massachusetts General Hospital and co-author of the Harvard Health Publishing book FASTMINDS: How to Thrive If You Have ADHD (or think you might).

On call

Q. For the past few months, I get dizzy when I turn my head quickly or bend over. What could cause this?

A. You most likely have a bothersome, but not serious, condition called benign paroxysmal positional vertigo. The symptoms are brought on by head movement. They can be quite mild, with just a few seconds of a spinning or off-balance sensation when the head moves a certain way, but some people experience severe dizziness, along with nausea and possible falling.

There are ways to shorten flare-ups and, in some people, prevent them from recurring.

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Psoriasis is a big star on TV drug ads, but this autoimmune skin disease is something most people try to keep well hidden.

"Psoriasis is among the most common skin conditions, affecting about 2% of the U.S. population, and while the condition doesn't affect everyone the same way, the approach to treatment and prevention is often similar," says Dr. Gideon Smith, an assistant professor of dermatology at Harvard-affiliated Massachusetts General Hospital.

Ketamine offers a new option for people with stubborn depression that doesn't respond to other medications.

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Many people know of ketamine as a hallucinogenic and addictive street drug, which, when abused, can put people in medical peril. But today, doctors are increasingly looking to ketamine as a potentially lifesaving treatment for people with severe, treatment-resistant depression, who may be at high risk for suicide.

"Ketamine has been shown to be effective in people who have not responded to antidepressant treatment," says Dr. Cristina Cusin, an assistant professor of psychiatry at Harvard Medical School. The fast-acting treatment has shown promise — sometimes improving depressive symptoms within hours of the first intravenous treatment.

Ask the doctors

Q. My sister, who is in her 50s, has always been very weight-conscious, but she recently went through a divorce and now seems unnaturally fixated on her weight and dieting. She's lost a substantial amount of weight. I've always thought of eating disorders as something that affects teenagers, but is it possible that she has one?

A. It is possible that your sister is suffering from an eating disorder, because they can affect people of any age, including older women, according to the American Psychiatric Association. They may be prompted by stress or a life change, such as a divorce. Signs that may indicate that a person has an eating disorder are

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Q. I know that some viruses live permanently inside us, but only make trouble now and then. I even heard recently that they might be a cause of Alzheimer's disease. Why do they sometimes cause disease, and can we keep that from happening?

A. We live all of our lives with various microorganisms on us and inside us. One example is the herpes family of viruses. Out of more than a hundred herpesviruses, there are nine that infect humans. Once we get infected with these viruses — usually early in life — they remain with us, "asleep" inside some of our cells. But periodically, they "wake up" (reactivate), start producing multiple copies of themselves, and infect other cells. That's what's happening when a cold sore suddenly forms on your lip.