Alzheimer's Disease Archive

Ask the doctor

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Q. I'm an 87-year-old man. Over the past year I've lost considerable weight, and I didn't have that much to lose. My doctor can't find any reason for my weight loss and is advising me to eat ice cream. But isn't that risky for my heart?

A. I smiled when I read your letter, because I've occasionally said that if I were to develop a terminal condition, the silver lining on that cloud would be that I could finally eat all the hot fudge sundaes I wanted.

News briefs

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Exercise is considered the most effective pill-free treatment to cope with the pain and stiffness of arthritis. And more people are getting advice from their health care providers about how to stay active, according to a study published online Jan. 5, 2018, by the CDC's Morbidity and Mortality Weekly Report. Researchers looked at national health surveys gathered from 2002 to 2014. In that period, there was an increase in the proportion of people with arthritis (osteoarthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia) who said their clinician suggested physical activity to help reduce symptoms — from 52% in 2002 to about 60% in 2014. But by 2014, about 40% of arthritis sufferers still said they weren't getting exercise counseling. That's significant, considering that 91 million people ages 18 or older are affected by arthritis, according to a study published online Nov. 27, 2017, by Arthritis & Rheumatology. You don't have to wait for a doctor to suggest exercise as an arthritis treatment. Try something gentle, like walking, tai chi, or modified yoga. For more ideas, check out the Harvard Special Health Report The Joint Pain Relief Workout (www.health.harvard.edu/jprw).

On call

Q. There has been a lot of talk about the severity of this flu season, and I recently heard that influenza also can trigger a heart attack. Should I worry?

A. Influenza is responsible for about 10,000 to 20,000 annual deaths, mostly from pneumonia or internal organ failure. In other situations, influenza infection strains a person's health, which can worsen underlying conditions, such as heart disease.

In the journals

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Migraine sufferers may be able to prevent future attacks with a new medication called galcanezumab, suggests a study published online Dec. 18, 2017, by JAMA Neurology. Currently, there are five FDA-approved drugs for migraines, but none were designed specifically for treating attacks or addressing the mechanisms at work.

In comparison, galcanezumab works to suppress the activity of calcitonin gene–related peptide (CGRP) in people. That molecule is believed to play an integral role in migraines and cluster headaches.

The way you live, what you eat and drink, and how you treat your body can affect your memory just as much as your physical health and well-being. Here are five things you can do every day to keep both your mind and body sharp.

1. Manage your stress. The constant drumbeat of daily stresses such as deadline pressures or petty arguments can certainly distract you and affect your ability to focus and recall. But the bigger problem is an ongoing sense of anxiety — that can lead to memory impairment. If you don't have a strategy in place for managing your stress, protecting your memory is one reason to get one. Deep breathing, meditation, yoga, and a "mindful" approach to living can all help.

The health risks of loneliness and isolation have been known for some time, but more recently research has shown the specific effects in the brain. Finding ways to make connections with other people is the best "medicine" to alleviate the mental and physical effects of loneliness.

Ask the doctor

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Q. My doctor said I "almost" have an underactive thyroid, which puzzled me. Then she said I might benefit from treatment, which puzzled me more. How can you "almost" have a disease, and how can treatment be useful if you don't have the disease?

A. I can see how that might have been confusing. In fairness, it's a confusing situation, even for doctors. Let's take this in two parts. First, what's an "underactive thyroid"? The thyroid gland in our neck makes a hormone, called thyroid hormone, that travels throughout the body and affects every cell. If it is making the right amount of the hormone — if the blood levels are normal — then there's no problem. If it's making too much (an overactive thyroid), or if it's making too little (an underactive thyroid), those are problems that require treatment.

If you are noticing problems in yourself or a loved one, here's where to turn for help and support.

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You're talking with a friend about a movie you saw recently, but can't remember the actor's name. Last week you found yourself upstairs, but couldn't remember what you came up to look for. Your keys are always missing. You worry: are these normal memory lapses or early signs of Alzheimer's disease or another form of dementia?

"Because there has been so much attention paid lately to the aging baby boomer population, I think Alzheimer's disease is getting a lot of attention, which is leading a lot of people to believe they may have the condition," says Dr. Suzanne Salamon, associate chief of the gerontology division at Beth Israel Deaconess Medical Center and assistant professor of medicine at Harvard Medical School.

Symptoms of dry skin, eczema, contact dermatitis, and psoriasis can overlap.

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It's easy to overlook dry skin during the winter, when indoor heating and dry air pull moisture from the skin. But sometimes it's tough to tell if dry skin is a consequence of the season or a sign of a serious condition. "I see a fair number of people who come in with psoriasis or eczema and had just assumed it was dry skin," says Dr. Jason Frangos, a dermatologist at Harvard-affiliated Brigham and Women's Hospital.

Why does skin dry out?

It's not just winter conditions that lead to dry skin; it's also a change in our skin's top layer, or epidermis. This layer is normally thick with naturally occurring fats and oils that act as a barrier to help retain moisture and prevent irritants from entering the skin.