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Immune and infectious diseases Archive

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Can the flu shot hurt my immune response?

Ask the doctors


 Image: © scyther5/Thinkstock

Q. I've read that getting the flu shot annually will weaken my immune system over time. Is this true?

A. A study published in the March 1, 2017, issue of The Journal of Infectious Diseases investigated whether getting an annual vaccination against influenza (flu) can weaken your body's natural ability to protect itself from the disease. Past studies have raised similar concerns. Researchers at the University of Bergen in Norway followed 250 health care workers. Some of them got a flu vaccination every year from 2009 through 2013. The others only received the vaccine once in 2009 and not in the years from 2010 to 2013. The researchers then took blood samples before the influenza season (and before people were vaccinated that season), from the members of both groups and looked at different markers to gauge how well their immune systems would respond to the influenza virus. They found that getting an annual flu vaccination did not weaken the immune system. As a group, the people who got the flu shot annually appeared to have a better immune response to influenza than those vaccinated only once.

You got the COVID-19 vaccine? I have vaccine envy

Got vaccine envy? Not only has the pandemic upended our lives, differing state priorities and restrictions on eligibility for highly effective COVID-19 vaccines are fueling feelings of jealousy and unfairness that encourage questionable actions and ethics.

The tragedy of long COVID

Tens of thousands of people in the US have recovered from COVID-19 but continue to experience feelings of exhaustion, little energy, and mental fogginess that linger for months. Known as "post-COVID long haulers," they are grappling with uncertainty surrounding when –– and whether –– their health problems will resolve.

Why won't some health care workers get vaccinated?

COVID-19 vaccination rates among health care workers in nursing homes and long-term care facilities have been lower than expected. Is this an information problem or does it stem from other issues –– and what can be done?

Grandparenting: Anticipating March 11

It’s been almost a year since our lives were profoundly altered by the COVID-19 pandemic. For grandparents, marking this anniversary with their grandchildren can help them make sense of what they have been through. Asking them questions will help determine how best to commemorate the day.

Which test is best for COVID-19?

So much about testing for COVID-19 is confusing—from the types and number of tests available to woefully incomplete information about testing and the changing options. Understanding the current choices can help you make an informed decision about how to proceed if you want to be tested.

Good news: Deaths due to HIV are way down

A new study cites a remarkable decline in deaths due to HIV infection, and dramatically fewer new cases of HIV infection in the US over the past decade. But there is still a long way to go before declaring victory over HIV/AIDS.

Vaccines for COVID-19 moving closer

Scientists around the world are trying to engineer safe, effective, long-lasting vaccines to help the body block the virus that causes COVID-19. Three vaccine approaches out of more than 100 are among the first to be tested clinically in the United States.

Driving equity in health care: Lessons from COVID-19

The coronavirus pandemic has forced health care organizations to confront the inequities in their systems, particularly those affecting immigrants and communities of color. But once the disparities are acknowledged, what practical steps can be taken to address them?

Does lupus or arthritis affect your prognosis if you get COVID-19?

People with certain chronic conditions are at increased risk for severe COVID-19. These include a compromised immune system, which can happen for a number of reasons. Many people with rheumatoid arthritis or lupus take drugs that suppress the immune system, and new research examined the risks associated with such a situation.

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