Medical devices Archive

Semaglutide (Ozempic, Wegovy), which mimics a natural hormone called GLP-1, has become a popular obesity drug because it promotes dramatic weight loss. New evidence suggests this drug and others like it may also curb compulsions for things other than food. The drugs may also dampen cravings for alcohol, smoking, gambling, and excessive shopping by hampering activation of the brain's reward pathways. If further research confirms preliminary findings, the demand for GLP-1 drugs is likely to increase.

Continuous positive airway pressure (CPAP) is a first-line treatment for people with obstructive sleep apnea. The CPAP keeps the airway open by pushing a forceful stream of air through a tube and into a mask worn during sleep. The air comes from a small bedside pump (an air compressor). Other forms of positive airway pressure (PAP) may be helpful for people with central sleep apnea. Doctors determine which type of PAP therapy and device someone needs. Patients select the type of PAP mask to use with the system.

Abruptly stopping a medication can be risky and even life-threatening. For example, suddenly discontinuing certain drugs can cause a rebound effect, meaning that symptoms or problems that were controlled—such as high blood pressure or heartburn—can return with a vengeance. Stopping some medications, such as prescription painkillers or antidepressants, might result in withdrawal symptoms. Before quitting any drug cold turkey, it's important to consult with a doctor to make sure that it's safe.

A newer class of medications used to treat type 2 diabetes called glucagon-like peptide-1 (GLP-1) receptor agonists has gained attention because of their impressive weight-loss results—in many cases, 10% to 20% of a person's body weight. Versions of two of these GLP-1 receptor agonists, liraglutide (Saxenda) and semaglutide (Wegovy), are FDA-approved for weight loss, even for people without diabetes. However, there isn't enough evidence to know whether these drugs might be beneficial or dangerous for people who are not diagnosed with diabetes or obesity.

Vasomotor symptoms, consisting of hot flashes and night sweats, affect 80% of women during the menopause transition and beyond. In May 2023, the FDA approved fezolinetant (Veozah) as the first nonhormonal medication designed specifically for vasomotor symptoms. Other medications deemed effective for hot flashes are prescribed off-label. They include selective serotonin reuptake inhibitors, oxybutynin, and gabapentin. But these drugs may lead to troublesome side effects. Women interested in hot flash relief should ask their clinicians for options that take into account their other symptoms.

Taking a blood thinner helps protect people at risk for dangerous blood clots that can lead to life-threatening conditions, such as a stroke or heart attack. But the medications increase the risk for uncontrolled bleeding. People taking the drugs should learn what to do in case bleeding occurs. For minor injuries, it's important to apply extra pressure until bleeding stops. For serious injuries, one should call 911 and apply as much pressure as possible to the wound until help arrives. People who take blood thinners and experience even minor injury from a fall or accident should automatically go to urgent care or the emergency department to get checked out, even if there is no apparent bleeding or trauma is observed.

Contrary to its reputation as an anti-aging supplement, human growth hormone is not effective at turning back the clock, and it may carry health risks. Commitment to a healthy diet and regular exercise is still the best formula for healthy aging.

Some medical alert systems now have advanced technology that integrates monitoring services with a smartphone, smart watch, or smart speaker. The services aren't cheap. They range from $20 to $50 per month, depending on the company and any additional services (such as fall detection). There may also be fees for activation and equipment (up to a few hundred dollars). The alternative is getting an alert system that isn't monitored, such as free "panic button" apps for smartphones or a smart watch that can notify relatives in an emergency.

Some medication instructions are vague and confusing. Examples include "take once daily," "take with food," and "take with water." When someone is unsure exactly how to take a medication, even if it's already been explained, it's best to ask for clarification. Ideally this happens when a doctor writes the prescription, but it's okay to call and ask later. It may also be helpful to ask a pharmacist for the directions, either when picking up a medication or on a later call.

A nasal spray containing the experimental drug etripamil can quickly treat an abnormally fast heart rhythm called supraventricular tachycardia. The disordered rhythm occurs sporadically and can raise heart rate to as much as 200 beats per minute.