Stroke Archive

PrEP (pre-exposure prophylaxis) is a daily medication taken to prevent HIV infection. While multiple studies show PrEP is effective, relatively few of those who might benefit are taking it. Will a 10-year initiative to reduce rates of HIV and a new formulation of PrEP help?

Doctors say three recently approved migraine prevention drugs are helping people have fewer headaches.

For people with frequent, debilitating migraine headaches, 2018 brought encouraging news. The FDA approved three new medications — erenumab (Aimovig), fremanezumab (Ajovy), and galcanezumab (Emgality) — the first drugs designed specifically to prevent migraines and reduce their frequency, intensity, and duration.

It was a big development, since other medications used to stop migraines were created to control other conditions, such as seizures, depression, high blood pressure, or an irregular heartbeat. But their side effects (such as weight gain, dizziness, or fuzzy thinking) often cause people to skip treatment.

Ask the doctors

Q. I've had endometriosis since I was in my 30s. I'm now approaching menopause. Will my symptoms get better or even go away after menopause?

A. Possibly, but not always. Endometriosis is a condition in which tissue that resembles the tissue that lines the uterus, called endometrial tissue, grows in other locations inside the body. Typically, it grows on structures and organs in the pelvis, such as the ovaries, fallopian tubes, bladder, or bowels. When a woman menstruates, this tissue behaves like the lining of the uterus and bleeds. But because this blood has no way to exit the body, it pools inside. This leads to pain, inflammation, and scarring.

Some men with an enlarged prostate gland (benign prostatic hyperplasia, or BPH for short) eventually start to experience urinary incontinence, the involuntary discharge of urine. The incontinence can be related to overactive bladder, one of the changes in bladder function caused by BPH.

Normally, the brain says "time to go" when your bladder is only partially full. That gives you a fair warning to find a place to relieve yourself. When you decide to let go, a valve called the urinary sphincter opens to allow the bladder to drain. Muscles in the bladder wall squeeze inward to empty the storage tank.

Nerve damage might be causing everything from low blood pressure to gastrointestinal distress without your knowing it.

Doctors have long known peripheral neuropathy as a nerve condition that causes reduced sensation, tingling, weakness, or pain in the feet and hands. But those symptoms may be just the tip of the iceberg. Doctors are now learning that neuropathy can cause many more problems.

What is peripheral neuropathy?

Peripheral neuropathy refers to damage to the peripheral nerves throughout the body. These nerves carry messages to and from the brain.

Research we're watching

Eating ultra-processed foods — such as packaged snacks, sugary cereals and drinks, chicken nuggets, and instant soup — may leave people more prone to heart disease and an early death, two new studies suggest. Both were published May 29 in The BMJ.

One study followed more than 105,000 adults for just over five years. Researchers found that for every 10% increase in the amount of ultra-processed foods people ate, their risk of a heart attack, stroke, or other serious cardiovascular event was 12% higher. The other study tracked nearly 20,000 people over an average of 10 years. People who ate more than four servings of ultra-processed foods daily had a 62% higher risk of dying from all causes compared with those who ate only two servings per day.