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IBS in the crosshairs

Irritable bowel syndrome (IBS) affects up to 45 million Americans, two-thirds of whom are women. IBS is categorized into three types depending on which symptoms dominate: diarrhea, constipation, or a mix of both. Possible contributors include changes in gut bacteria, faulty nerve signals between brain and intestine, pelvic floor problems, and genetics. Newer treatment approaches target pathways involved in symptoms. Doctors are also repurposing older drugs for IBS, including certain antidepressants and the antibiotic rifaximin (Xifaxan).

Was it something you ate? Follow these steps when food makes you sick

Symptoms of food-related illness can show up hours or even days after ingesting a harmful microbe or toxin. Symptoms of food-related illness might include intense nausea, vomiting, stomach cramps, diarrhea, or possibly a low-grade fever (below 101° F). Someone with food-related illness should rest as much as possible, stay hydrated, and avoid sugary drinks or alcohol. A person who develops a high fever, bloody stool, severe abdominal pain, or severe dehydration should go to the emergency room.

Do our microbes affect our behavior?

Scientists wonder if gut microbes might influence behavior in animals, including humans. Some studies suggest a link. For example, a 2022 study suggested that gut microbes can influence an animal's motivation to exercise. Scientists speculate that the same might be true in humans. Other studies have found that a parasite called Toxoplasma gondii is tied to risky behavior in lab mice and risk-taking behaviors in humans. Scientists now even consider it conceivable that gut microbes might influence things like human intelligence, attitudes, empathy, and more, although the idea has yet to be proved.

Fighting the most common skin cancers

The most common non-melanoma skin cancers are basal cell carcinomas and squamous cell carcinomas. They aren’t usually life-threatening, but they can be quite dangerous. They can bleed, hurt, and eat away at skin. If left untreated, they can erode through important structures like the nose, eyes, bones, or muscles. If they become very large, they can spread, and in rare cases cause death. Treatment ranges from scraping out skin cancers with surgical tools to Mohs surgery, a procedure that spares as much healthy skin as possible.

COVID-19 or something else?

Many COVID-19 symptoms — such as fever, cough, or muscle aches — overlap with the symptoms of other respiratory conditions, such as influenza, a common cold, or asthma. But there are differences among the conditions. For example, a bout of the flu or a cold will not cause shortness of breath the way COVID-19 will. And while asthma can cause shortness of breath, it won't cause a fever or body aches the way COVID-19 will. A person who's experiencing concerning symptoms of respiratory illness should report them to a doctor.

Prostate cancer in transgender women

The increasing size and visibility of the transgender population has implications for public health. Hormone treatment given to transgender women lowers the overall risk of prostate cancer, but the risk of a trans woman developing the disease is not zero.

Can long COVID affect the gut?

Some people who have been infected with the virus that causes COVID-19  have experienced lingering effects like low energy and brain fog. Could gastrointestinal problems be another aftereffect of the virus?

Late-stage cervical cancer on the rise: What to know

Cervical cancer is curable when caught early through routine screening, so research showing a surprising rise in advanced cancer cases in some groups is worrisome. Two Harvard experts share insights about the research and advice on how people can best protect themselves.

A pain in the rear

Everyone is born with the blood vessels that underlie hemorrhoids, but they may become problematic when they enlarge. Half of people have symptoms by age 50 that include pain, itching, swelling, and bleeding. Home remedies such as pain relievers, topical creams and ointments, sitz baths, and cold compresses don't eradicate hemorrhoids. In-office procedures can cut off blood supply to internal hemorrhoids, allowing them to fall off. Surgery is the only definitive treatment option for external hemorrhoids visible at the anus.

Healthy gut, healthy heart

The gut is home to trillions of microbes, collectively known as the gut microbiota, which help with digestion, manufacture certain nutrients, and release various substances that have wide-ranging health effects, including on cardiovascular health. As diet plays a significant role in the composition of the gut microbiota, people's diet can indirectly affect heart health. Following a plant-based diet that emphasizes less red meat and more fiber can support the gut and its heart-healthy benefits.

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