Medications and treatments Archive

The 2025 blood pressure guidelines recommend starting drugs to treat hypertension if people don't meet blood pressure goals after three to six months of lifestyle changes. The guidelines also recommend that everyone with high blood pressure be screened for primary aldosteronism, and suggest that people with resistant hypertension (stubbornly high blood pressure) consider renal denervation, a procedure that disrupts some of the nerves around the arteries supplying blood to the kidneys.

A 2025 analysis of 19 randomized controlled trials involving 6,500 people found that tramadol, a widely prescribed opioid drug, was only mildly effective at reducing chronic pain. It increased the risks for both mild and serious side effects, including heart problems.

Men who could benefit from therapy often resist it because it carries a negative stigma for them and they feel uncomfortable about seeking help. For these individuals, cognitive behavioral therapy (CBT) may be an option. Many men find CBT appealing because it is short-term, structured, and focused on current issues. CBT is regularly used to treat depression and anxiety disorders, but it can help with managing other common ailments, such as insomnia, chronic pain, irritable bowel syndrome, chronic fatigue syndrome, fibromyalgia, and migraines.

Home health technologies have made it easier for people to monitor their health at home. These handy home devices can track certain health markers, such as blood pressure, blood sugar, heart rhythm, heart rate variability, and oxygen saturation. Checking this information periodically may help some people identify possible problems or manage existing conditions.

Increasing numbers of older adults are using cannabis over recent years. People over 50 report using it to relax, sleep better, feel good, relieve pain, improve mood or mental health, or treat medical conditions. But older adults are more vulnerable to cannabis side effects, such as falls or interactions with prescription and over-the-counter drugs. Many older adults aren't aware that cannabis products today are far more potent than in decades past. Medical visits related to cannabis use rose more than 27-fold among adults 65 and older between 2008 and 2021.

The long-term outlook for men diagnosed with prostate cancer continues to improve. These medical advances, however, have also drawn attention to the mental health challenges many survivors encounter. It's still common for survivors to struggle with loss of masculine self-esteem and changes in body image.

The term ototoxicity describes inner ear damage from drugs that can cause tinnitus (ringing in the ears), and affect hearing and sometimes balance. Medications more likely to cause ototoxicity include aspirin; the antibiotics azithromycin and clarithromycin; certain chemotherapy drugs; loop diuretics such as furosemide (Lasix); and some biologics. These drugs can damage hearing by injuring hairlike projections in the inner ear. People taking ototoxic drugs should get their hearing tested before, during, and after using the drug.

Women over 60 need less iron than they did before menopause, when they lost iron through menstruation. Many conditions can lead to iron loss and iron-deficiency anemia, when the body can’t make enough red blood cells to properly carry oxygen throughout the body. Signs of iron deficiency include pale skin, fatigue, shortness of breath, weight loss, and chest pain. Tests can reveal iron deficiency and underlying reasons for iron loss. People should not take iron supplements without checking with their doctor. Too much iron can damage organs.

Doctors have long prescribed drugs called beta blockers to all heart attack survivors. These drugs, which slow down the heart and lower blood pressure, include atenolol (Tenormin) and metoprolol (Lopressor, Toprol). Growing evidence suggests that these drugs offer no meaningful benefit for people whose hearts still pump normally after a heart attack. Sometimes, however, a heart attack leaves the left ventricle (the heart’s main pumping chamber) unable to contract effectively. When that’s the case, beta blockers are still recommended.

Four classes of drugs commonly prescribed to older adults-opioids, benzodiazepines, gabapentinoids, and antidepressants-may be driving the dramatic rise in deadly falls over the past three decades. Known as fall risk-increasing drugs (FRIDs), these drug classes affect brain function and can make people feel sleepy, dizzy, or confused-all of which can leave them vulnerable to falling. People currently taking these drugs shouldn't stop taking them abruptly, as doing so may cause withdrawal symptoms. People should ask their primary care clinician to review all their medications at least once a year.