Medications and treatments Archive

An inexpensive blood test that checks for a genetic variant of Lp(a)-a fatty particle similar to LDL cholesterol-may help clarify who might benefit from a daily low-dose aspirin, according to a 2025 review of study findings.

There are currently nine trials of vaccines for Alzheimer's disease under way. All of them are in people with mild Alzheimer's or with the pre-Alzheimer's condition called mild cognitive impairment. All of the vaccines are designed to encourage the immune system to remove protein deposits from the brain. Most experimental vaccines are given by injection; one being tested at Harvard Medical School uses a nasal spray. It will be several years before we know if any of them will work.

Wearable fitness trackers like smart watches offer measurable and motivating data for exercise routines and safety, especially for people with heart conditions. Features include movement reminders, step counts (a daily total of 4,000 to 7,000 steps is considered beneficial), heart rate zones for exercise intensity, and measurements of heart rate recovery and variability to assess overall heart health. These tools can help optimize workouts and reveal potential issues.

In robotic surgery, a surgeon controls robotic instruments that perform the operation, based on what the surgeon sees on a TV monitor. This type of surgery has many advantages: it involves small incisions, better views inside the body, and better range of motion than human hands. A research letter published in the May 2025 issue of JAMA Neurology described how robots controlled by a distant surgeon could reach in, grab, and remove blood clots stuck in a brain artery, reducing the damage from a stroke.

The four types of anesthesia include local anesthesia, regional anesthesia, monitored anesthesia, and general anesthesia. Before getting anesthesia, one should ask the doctor which type of anesthesia will be administered, what its risks are, and if delirium is a high risk. One should also ask how to prepare for anesthesia in the days leading up to a procedure-whether medications might need to be temporarily halted, when to stop eating or drinking before surgery, and whether to schedule measures to help reduce delirium.

A 2025 randomized controlled trial found that GLP-1 receptor agonists, the blockbuster drugs approved to treat diabetes and obesity, boosted the walking ability of people with diabetes and peripheral artery disease (PAD) in the legs. The news is encouraging, since there are few effective treatments for PAD-reduced blood flow in the limbs that leads to pain with activity. However, it will take more evidence before doctors feel comfortable prescribing GLP-1s if a person only has PAD.

While many health symptoms resolve quickly on their own, others linger and make people wonder if they need to see a doctor. Symptoms that warrant a doctor's visit include drawn-out cold symptoms such as fatigue, cough, and low-grade fever; a fever lasting more than four days; unexpected symptoms when starting a new medication or after surgery; certain digestive problems; and new or worsening mental health issues.

Semaglutide, a GLP-1 agonist used to treat diabetes and obesity, may also help people with metabolic dysfunction-associated steatohepatitis, a severe stage of fatty liver disease, suggests a 2025 study.