Breast Cancer Archive

In the journals

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While it's important to have any suspicious mole checked for possible skin cancer, a study published online Aug. 29, 2017, by the Journal of the American Academy of Dermatology suggests most melanomas — the deadliest skin cancer — appear as new spots on the skin. The researchers reviewed 38 studies involving 20,126 cases of melanoma and found that 29% of diagnosed melanomas came from an existing mole, while 71% appeared as new spots. Moreover, they discovered that melanomas that grew from moles were thinner and thus less aggressive than other melanomas. In fact, people whose melanoma was associated with a mole had a better prognosis than others.

The study's authors stressed the importance of looking for any new spots on the skin as well as checking moles for changes, like itching or bleeding, and to see a dermatologist if needed. The American Academy of Dermatology encourages everyone to perform regular skin self-exams, and to ask a partner to check hard-to-see areas like the back. You can learn how to do a skin self-exam, and much more, at www.aad.org/public/spot-skin-cancer.

Ask the doctors

Q. Is there any way to tell if you are getting osteoporosis? Are there symptoms?

A. Osteoporosis is a disease that causes your bones to become weak and brittle and more likely to break. Unfortunately, you probably won't have any symptoms until the disease is advanced or you actually experience a fracture. However, there are two visible clues of osteoporosis: changes in your posture (such as a hunched-over appearance) and loss of height. Both of these changes may be caused when your spine becomes curved or compressed from weakness or tiny fractures (called compression fractures) in your vertebrae, the small bones that make up your spine.

It's called "weight bias," and even health care providers aren't immune.

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If you've ever delayed a doctor's appointment so you could lose a few pounds before your annual weigh-in, or hesitated to exercise in public because you felt self-conscious among a sea of hard-bodied gym goers, your weight may be affecting your health — but not in the way you might think.

Even if you're otherwise healthy, sometimes excess pounds bring increased health risks, especially if they keep you from following recommended health practices that offer protection over the long term.

Research we're watching

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To catch skin cancer early, be on the lookout for new spots on your skin. A recent study found that more often than not, melanoma occurs as a new spot on your body — not as changes in an existing mole. The study, published online August 29 by the Journal of the American Academy of Dermatology, found that only 29% of melanomas came from an existing mole on the body that changed. In 71% of cases, melanoma occurred in a new lesion that popped up in a new place on the skin. In addition, the study authors noted that melanomas that do occur in existing moles tend to be thinner than melanomas in new lesions.

In addition to looking for new and unusual spots on your skin, remember your ABCDs to spot the signs of melanoma:

Research we're watching

Good news on the cancer front: The cancer death rate dropped 35% between 1991 and 2014 among children and 25% in adults, according to the annual American Association for Cancer Research Cancer Progress Report. And more treatments for the disease are on the horizon. The FDA has recently approved nine new cancer treatments and signed off on expanding the uses of eight existing therapies to treat different types of cancer. Among the new treatments are innovative immunotherapeutics, which help some people with cancer live longer with a better quality of life; an imaging agent that will let surgeons more precisely remove brain tumors; and molecularly targeted agents, which take aim at specific molecules that help cancers grow and spread to other areas of the body. It is hoped that these new treatments will further reduce cancer deaths. To read the full report, go to cancerprogressreport.org.

Screening tests for lung and breast cancer—chest computed tomography (CT) scans and mammograms—may offer clues about a person’s risk of heart disease.

In the journals

Smoking causes lung cancer — no surprise there. But a new study found that high dosages of vitamin B6 or B12 supplements were associated with three to four times the lung cancer risk in male smokers compared with smokers who did not take the supplements. The results were published in the Aug. 22, 2017, Journal of Clinical Oncology.

Researchers examined information from more than 44,000 men ages 50 to 76. At enrollment, the men reported on their smoking history and their B vitamin supplement use over the previous 10 years. In the study, high intake of B vitamin was classified as 20 milligrams (mg) of B6 per day or 55 micrograms (mcg) of B12. (The recommended daily intakes for men ages 51 and older are 1.7 mg for B6 and 2.4 mcg for B12.)

As a group, men have nudged down their stroke numbers over the past decade. Why haven't women seen the same improvement?

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Men are less likely to have strokes than they were 10 years ago, but the risk for women has stayed about the same, according to a study of stroke data from Ohio and Kentucky, published online on August 21 by Neurology.

The question is, why?

"This study raises important concerns about the lack of decline in stroke rates in women," says Dr. Kathryn M. Rexrode, associate professor of medicine and chief of the Division of Women's Health at Harvard Medical School. Study authors suggested it's likely that better treatments for high blood pressure, high cholesterol, and diabetes, and a reduction in the number of people smoking helped to reduce the risk for men for having the most common type of stroke — ischemic stroke, which is typically caused by a clot that blocks blood flow to the brain. But women, who in theory should benefit from the same interventions, didn't see any improvement in their stroke rates over the study period.

All women, regardless of risk, should focus on preventing diabetes.

Can a blood test act as a crystal ball, alerting you to a health hazard that may await you down the road? Researchers say they've found one that may do just that for diabetes. It could help predict whether women — even ones with no other signs of the disease — may develop the condition in the future.

In a study published online June 21 by the Journal of Clinical Lipidology, researchers showed that in many cases, a test called lipoprotein insulin resistance (LPIR) did a better job, at predicting which women would go on to develop diabetes, says Dr. Samia Mora, one of the study authors and associate professor of medicine at Harvard Medical School. In many cases, it was more accurate than traditional measures — such as

Experts says it's too early for alarm, but the findings provide another good reason to pay attention to oral health.

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Is gum disease linked to cancer? A study published in the August issue of Cancer Epidemiology, Biomarkers & Prevention suggests a tie between the two, finding that older women with gum disease had a higher risk for cancers of the breast, lung, and esophagus as well as melanoma, the most dangerous form of skin cancer.

But it's not time to sound the alarm just yet, because while the study was published in a well-regarded journal, it had limitations that may have affected the results, says Alessandro Villa, instructor in oral medicine, infection, and immunity at the Harvard School of Dental Medicine and associate surgeon at Brigham and Women's Hospital. Even so, he says, your oral health should still be a top priority because while it may be premature to say gum disease and cancer are linked, research has shown that gum disease, also known as periodontal disease, may increase the risk of heart disease and other health problems.