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FDA approves new drug for men at high risk of prostate cancer spread

Men whose PSA levels continue rising even after surgery or radiation therapy may have a new treatment option with the approval of the drug apalutamide.

A new approach to cancer diagnosis

Liquid biopsies may offer a less invasive alternative than a traditional biopsy.


 Image: © fotoquique/Getty Images

A tissue biopsy is the standard test for identifying cancer. Your medical team will use needles or other devices to capture pieces of actual tumor to see if it's malignant or benign. But another approach, called a liquid biopsy, is less invasive and may provide a diagnosis when a biopsy doesn't.

This test uses a person's blood to look for signs of cells or mutated DNA that a tumor has shed into the bloodstream. "By sampling DNA or circulating tumor cells in the blood, we can predict and monitor responses to cancer treatments without subjecting patients to invasive biopsy procedures — and perhaps detect cancer early, before it has had a chance to spread," says Dr. David Miyamoto, assistant professor of radiation oncology at Harvard Medical School.

Screening can often prevent colon cancer

Research we're watching


 Image: © Catherine Lane/Getty Images

March is National Colorectal Cancer Awareness month. Have you been screened? Colon cancer is the second leading cause of cancer deaths in the United States, but is also highly preventable through recommended screenings. These screenings enable doctors to spot precancerous lesions that can lead to colon cancer and remove them before they become a problem. Screenings can also find cancers early, when they are most treatable. All people ages 50 to 75 should get recommended colon cancer screenings. Some people should start getting screened earlier if they have certain risk factors for colon cancer, including a family history, a personal history of inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), or a genetic condition that makes colon cancer more likely (such as familial adenomatous polyposis).

There are several tests used for colon cancer screening, including colonoscopy, which uses a device to examine the full length of the colon and rectum; stool tests; flexible sigmoidoscopy, which uses a device to examine a portion of the colon; and CT colonography, a scanning technique that produces images of the colon that are examined by the doctor.

Is that dry skin really something more serious?

Symptoms of dry skin, eczema, contact dermatitis, and psoriasis can overlap.


 Image: © Sasha_Suzi/Thinkstock

It's easy to overlook dry skin during the winter, when indoor heating and dry air pull moisture from the skin. But sometimes it's tough to tell if dry skin is a consequence of the season or a sign of a serious condition. "I see a fair number of people who come in with psoriasis or eczema and had just assumed it was dry skin," says Dr. Jason Frangos, a dermatologist at Harvard-affiliated Brigham and Women's Hospital.

Why does skin dry out?

It's not just winter conditions that lead to dry skin; it's also a change in our skin's top layer, or epidermis. This layer is normally thick with naturally occurring fats and oils that act as a barrier to help retain moisture and prevent irritants from entering the skin.

Ward off winter skin woes

Try these simple strategies to keep dry, cracking skin at bay during the cold weather.

Chapped, dry, cracked, and peeling... winter can be hard on your skin. What with the cold air and the lack of humidity, your skin spends the winter months fighting to retain moisture, not to mention fending off other insults from cold-weather staples like scratchy wool clothes and crackling wood fires.

How can your skin survive the season? We asked Dr. Barbara Gilchrest, senior lecturer on dermatology at Harvard Medical School, to weigh in with her best tips to help you protect your skin from winter dryness.

Newer drugs are improving survival for men with metastatic prostate cancer

Men with prostate cancer that has spread outside the gland now have several newer drug options available for treatment, and research has found that taking any of them is likely to improve survival duration.

A more precise approach to fighting cancer

Precision medicine offers a personalized approach for prevention and treatment of cancer and other diseases.


 Image: © Pogotskiy/Thinkstock

If you have a stomachache or cold, you go to the pharmacy and grab the same remedy that everyone else uses, and it often works. But is that always the best approach? Your reaction to an infection may be quite different from someone else's, so perhaps you need a treatment designed just for you and your ailment.

That's the philosophy behind precision medicine (sometimes referred to as personalized medicine), an emerging approach to prevention and treatment that takes into account a person's genes, environment, and lifestyle and eliminates the one-size-fits-all approach to health care.

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