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What's the secret to living longer? A Harvard study published online April 30, 2018, by Circulation suggests that it may come down to five healthy habits: eating a healthy diet, exercising daily, keeping a healthy body weight, drinking alcohol only in moderation, and not smoking. Researchers combed through information from two large studies that tracked more than 123,000 men and women for about three decades. Scientists estimated that life expectancy for study participants (at age 50) was 79 for women and 75 for men, if they didn't maintain healthy habits. But if they adopted all five habits, life expectancy at age 50 jumped to 93 for women and 87 for men. And following even one healthy habit was associated with a lower risk for dying young. The study is only observational and doesn't prove that healthy habits extend your life. But the findings build on similar research. "It's never too late to make positive lifestyle changes. Even for those who are 70 or older, following a healthy lifestyle such as eating a healthy diet and being physically active can add more years to life," says Dr. Frank Hu, senior author of the study and chair of the Department of Nutrition at the Harvard T.H. Chan School of Public Health.

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Encouraging news for people who suffer with migraines: in May, the FDA approved erenumab (Aimovig), the first medication aimed at preventing these debilitating headaches. Current medications to treat migraines were actually designed to control other conditions, such as seizures or an irregular heartbeat; their side effects (like sexual dysfunction and fuzzy thinking) often cause people to skip treatment. Erenumab offers a new approach. Injected once a month, it works by blocking a molecule (calcitonin gene-related peptide) involved in migraine attacks, and compared with other drugs, it appears to have fewer side effects (primarily constipation and injection site reactions). "This drug is for people who have more than four migraines per month, but it won't take migraines away entirely," says Dr. Gad Marshall, a neurologist at Harvard-affiliated Brigham and Women's Hospital. Clinical trials suggest it can reduce frequency by one or two migraines per month, or even more in some people. "For people with frequent debilitating migraines it could be a game changer," says Dr. Lee Schwamm, a neurologist at Harvard-affiliated Massachusetts General Hospital. "But erenumab is expensive, and it will take time to find out if it's effective and safe over the long term."

Learn the most common sources of sodium in your diet and some easy substitutions you can make.

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If you think steering clear of potato chips, pretzels, and other savory snacks is the best way to trim salt from your diet, think again. Yes, those foods are salty — but they only rank no. 7 on the top 10 sources of sodium (a major component of salt) in the average American's diet.

The category of bread and rolls tops the list, which is based both on sodium content and how often people eat the foods. Bread is not especially salty, but we eat a lot of it, as well as similar foods such as hamburger and hot dog buns, bagels, and English muffins.

These drugs help prevent potentially life-threatening events. Make sure you're taking them correctly.

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Recently, a Heart Letter subscriber emailed us this query: "Does taking your blood pressure medication at night protect the heart more than if you take it in the morning? If so, why?"

Maybe you've wondered the same thing, or have other questions about the drugs you take to prevent or treat heart disease. In addition to blood pressure pills, these include drugs to lower cholesterol and to prevent blood clots.

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Vine-ripened, locally grown tomatoes are abundant in farmers' markets in August. Scientifically speaking, these vivid red (and sometimes yellow, brown, purple, or green) orbs are fruits. But the USDA, which issues the Dietary Guidelines for Americans, includes tomatoes in the red-orange vegetable group. Aim for about five to six cups per week of the foods in this group, which also includes carrots, squash, and sweet potatoes.

When good fresh tomatoes aren't available, canned tomatoes are a good substitute, especially in soups, stews, and pasta sauces. Eating tomatoes and tomato products may help lower cholesterol and improve blood vessel function, according to a 2017 article in Atherosclerosis.

Research we're watching

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The same diet that doctors recommend for dodging heart disease also may help preserve brain tissue, a new study finds.

Researchers scrutinized diet surveys from more than 4,200 people with an average age of 66 and ranked the quality of their diets on a scale of 0 to 14. A score of 14 was healthiest and included lots of fruits and vegetables, whole grains, nuts, dairy, and fish, but limited sugar. The volunteers provided data on other factors that might affect brain size, such as blood pressure, physical activity, and smoking. They also underwent brain scans to measure their brain size.

Eating five servings of fruits and vegetables can go a long way to protecting against heart disease and cancer.

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We've been told the importance of eating fruits and vegetables ever since childhood, and yet we still tend to ignore this nutritional advice. In fact, a CDC survey found that only 18% of adults eat the recommended five daily servings of fruits and vegetables.

"The main reason older men have trouble reaching this amount is lack of awareness," says Vasanti Malik, a research scientist in the Department of Nutrition of Harvard's T.H. Chan School of Public Health. "They are not always engaged in their nutrition or aware of the impact fruits and vegetables can have on their health."