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Plants are loaded with naturally occurring chemicals that appear to help health. And high, long-term intakes of certain kinds of plant chemicals called flavonoids are associated with a reduced risk for developing dementia, according to a study published online April 22, 2020, by The American Journal of Clinical Nutrition. Researchers evaluated the health information of 2,800 dementia-free people (average age 59) who periodically underwent physical exams, had lab tests, and answered diet questionnaires. After 20 years, people who had reported the highest flavonoid intake were about 40% less likely to develop dementia, compared with people who'd reported the lowest intake. There are many different types of flavonoids; those with the greatest link to lower dementia risk came from tea, apples, pears, blueberries, and strawberries. A high intake was about the same as having 7.5 cups of berries, eight apples or pears, and 19 cups of tea per month. A low intake was about the same as having no berries or tea and less than two apples per month. The study was observational and doesn't prove that high flavonoid intake protected people from developing dementia. But researchers say other evidence suggests flavonoids may ward off brain inflammation and protect brain cells.

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The United States is reporting increasing numbers of "deaths from despair" (suicide, drug overdose, or alcohol poisoning). Antidepressants and psychotherapy are often used to help people who are having a hard time coping with extremely difficult times and who are at risk for dying because of it. A recent Harvard study found that another strategy may also play a part in countering despair: attending religious services. The study, published online May 6, 2020, by JAMA Psychiatry, evaluated self-reported religious service attendance among 110,000 white, middle-aged men and women who were followed for about 30 years. Compared with never attending religious services, going at least once per week was associated with a much lower risk of death from despair: 68% lower for women and 37% lower for men. Researchers say that religious participation — regardless of affiliation — may serve as an antidote to despair and provide a sustained sense of hope, meaning, peace, and positive outlook. Also, faith-based organizations promote social engagement and connectedness and preach against self-injury and substance use. The study was observational and does not prove that regularly going to a religious service prevents death from despair. However, we know from other Harvard research that using religion to cope is associated with improved outcomes for people with severe psychiatric illness. Due to the pandemic, it may be difficult to attend your usual place of worship. Consider attending services via teleconference. If you attend in-person services, wear a mask and try to stay six feet away from others.

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You may be familiar with the claims featured on packages of old-fashioned oatmeal, which note that "As part of a heart-healthy diet, the soluble fiber in oatmeal can help reduce cholesterol." Guess what? Back in 2008, the FDA also approved the equivalent health claim for barley products.

In fact, barley contains about three times as much fiber per serving as oats. Barley is particularly rich in a type of soluble fiber known as beta glucan, which is recognized for its cholesterol-lowering abilities. Barley is also a good or excellent source of several vitamins and minerals.

Along with historically high unemployment rates, the COVID-19 pandemic has caused a significant increase in food insecurity for millions of Americans, and this problem disproportionately affects lower-income people and racial and ethnic minorities. Temporary measures have helped a bit to ease the situation, and new proposals could do more.

The popular painkillers known as NSAIDs include aspirin, ibuprofen, naproxen, and the prescription drug celecoxib. All except aspirin may slightly increase the risk of a heart attack, but naproxen appears to be the least risky.

With the increased stress caused by the the COVID-19 pandemic, prescriptions for medications to treat mental illnesses have increased, leading to potential shortages of certain psychiatric medications. This means that some people might need to discuss their options with their prescribing clinician.

Osteoarthritis pain can be debilitating. Strategies can help get you moving again.

Pain from osteoarthritis is more than just a nuisance. Knee pain, in particular, can not only keep people from exercising, but also have a chilling effect on their ability to participate in social activities, especially those that involve walking or traveling, says Elena Losina, the Robert W. Lovett Professor of Orthopedic Surgery at Harvard Medical School and co-director of the Orthopaedic and Arthritis Center for Outcomes Research at Brigham and Women's Hospital.

"In fact, the quality of life of a person with persistent pain due to knee osteoarthritis is similar to quality of life in women with metastatic breast cancer controlled by therapy," she says.

Research we're watching

Your diet may influence your breast cancer risk. An analysis of 20 studies by researchers from the Harvard T.H. Chan School of Public Health, which was published online April 6, 2020, by the journal Cancer, found that women who ate the most fiber were 8% less likely to go on to develop breast cancer compared with the women who ate the least.

The reduction in breast cancer risk was seen for both premenopausal and postmenopausal breast cancers, as well as different types of breast cancer, including those that were estrogen and progesterone receptor–positive and estrogen and progesterone receptor–negative. Researchers from the Harvard T.H. Chan School of Public Health said that that the reduction may be due to fiber's effect in reducing both blood sugar and estrogen levels in the body.

There are ways to manage ED without medication.

Erectile dysfunction (ED) is one of the more common health issues older men face, especially those with cardiovascular disease and diabetes. Some estimates suggest between 50% and 70% of men ages 50 to 70 experience mild to moderate ED.

ED is defined as difficulty achieving or sustaining an erection. It is often caused by a combination of physical and emotional issues. ED makes intercourse difficult, which can lower sex drive and desire, increase anxiety and depression, and affect a man's relationship with his partner.

Ten years ago, the Harvard Heart Letter published a story about the potential health benefits of chia seeds. At the time, people were more familiar with the ceramic figures known as Chia Pets (see www.chia.com) than the idea of chia seeds as a health food. But today, you can find these nutritious seeds in major grocery stores, sold in packages or in products such as crackers, cereals, energy bars, and beverages.

The small, black seeds are among the richest plant sources of the omega-3 fatty acid known as alpha-linolenic acid (ALA). Diets high in ALA have been linked to a lower risk of heart disease. Chia seeds are also high in insoluble fiber, which may help lower harmful LDL cholesterol levels.