Vitamins, minerals & supplements Archive

When it comes to understanding this link, the devil is in the details.

When we talk about LDL cholesterol, it's always described as bad or harmful — and with good reason. High blood levels of this artery-clogging substance boost the risk of heart disease, the nation's leading cause of death. The more you can lower your LDL cholesterol (through diet, exercise, or medications), the lower your risk of a heart attack. For heart attack survivors, national guidelines recommend aiming for an LDL cholesterol level of less than 70 milligrams per deciliter to prevent a second heart attack.

In the past year, however, two studies in the journal Neurology reported a higher risk of hemorrhagic (bleeding) stroke in people with LDL levels of 70 and lower. While that sounds worrisome, a closer look at the findings can put these results into perspective.

One of the first cultivated grains, wheat is now ubiquitous in the average American diet. In the United States, about 75% of all grain products (such as bread, pasta, tortillas, cakes, and pastries) are made with wheat. Unfortunately, most of these commonly consumed foods are made with white flour: wheat kernels that have been stripped of their outer bran and inner germ layers and milled into a fine powder. White flour is fortified with some of the vitamins and minerals removed during this refining process. But most of the fiber and other healthful plant-based chemicals found in intact whole grains are missing.

Eating more whole grains is linked to a lower risk of heart disease and cancer, which is why the federal dietary guidelines say to "make half your grains whole." But most people aren't even close to that goal. According to the CDC, whole grains account for only about 16% of the total grain-based food adults eat on any given day.

Research we're watching

A drug long used to treat a painful form of arthritis called gout may also benefit heart attack survivors, according to a new study.

Derived from the autumn crocus, colchicine (Colcrys, Mitigare) helps to ease the joint inflammation and pain that characterize gout. Because mounting evidence suggests that inflammation plays a role in heart disease, researchers have tested various anti-inflammatory drugs in heart patients. The latest study, published online Nov. 16, 2019, by The New England Journal of Medicine, tested colchicine against a placebo in 4,745 people who had experienced a heart attack within the previous month. All the participants also took standard drugs to treat heart disease, including statins, aspirin, and other clot-preventing drugs.

Research we're watching

Younger adults who use marijuana appear to face a higher risk of stroke compared with those who don't use the drug, according to a report published Nov. 11, 2019, in the journal Stroke.

Researchers pooled data from a nationally representative survey from the CDC that included nearly 44,000 participants ages 18 to 44. About 14% reported using marijuana within the past month. Young adults who recently used marijuana were 1.8 times more likely to experience a stroke compared with nonusers. The risk was 2.5 times higher among frequent users (more than 10 days a month). Frequent marijuana users who also smoked regular cigarettes had three times the risk for nonusers.

A recent study suggested that eating red or processed meats won't necessarily harm your health. What is the truth?

The news headlines were everywhere: "It's Okay to Eat Red Meat." The source for this statement was a study published online Oct. 1, 2019, in Annals of Internal Medicine.

An international team of researchers conducted five systematic reviews that looked at the effects of red meat and processed meat on multiple health issues, such as heart disease, cancer, diabetes, and premature death.

On call

Q. I started having side effects from a prescribed drug. I stopped taking it, but the side effects are still there. How long does it take for a drug to be out of your system?

A. Most drugs will be out of your system quite quickly, but the symptoms of side effects may remain for some time. It depends on the medication and what kind of side effect has developed. The majority of prescription drugs are cleared out of your body rapidly by your kidneys and liver. Trace levels of a medicine may remain in the system while the liver and kidneys finish their filtering job. But these levels are often too low to have any noticeable effect. Patients with kidney or liver disease, however, can continue to have elevated blood levels of a drug even after stopping it.

In the journals

People with high blood pressure may benefit from taking their antihypertension medication at bedtime instead of the morning, according to a study published online Oct. 22, 2019, by the European Heart Journal.

The researchers looked at about 19,000 people (most of them men) who took blood pressure medication. Participants took their daily dose either upon waking or before going to bed. Everyone's blood pressure was checked over 48 hours once a year for six years.

Urinary tract infections can be dangerous. Here's how to recognize, treat, and prevent them.

More than 2.8 million antibiotic-resistant infections now occur in the United States each year, according to a CDC report published in November 2019. Among them are a growing number of urinary tract infections (UTIs) that can no longer be treated with the most common antibiotics.

"Antimicrobial-resistant UTIs are on the rise and have been since the early 2000s," says Dr. Lisa Bebell, an instructor in medicine at Harvard Medical School and an infectious diseases specialist at Massachusetts General Hospital. This trend is especially concerning for women because UTIs are so common: one of every two women will have a UTI in her lifetime.

Research we're watching

People living in rural areas of the country appear to be more likely to die from preventable causes compared with people in more urban locations, says a CDC report. The report looked at deaths from 2010 to 2017 and found that people in rural locations were more likely to die from preventable conditions, including cancers and heart and respiratory diseases. In 2010, about 29% of cancer deaths in rural areas were potentially preventable, compared with 18% of cancer deaths in urban areas. In addition, 45% of heart disease deaths in rural locations were deemed preventable, compared with 24% of heart disease deaths in urban areas. The authors suggested several strategies to reduce disparities, including better screening programs and initiatives to encourage better eating and exercise habits, as well as smoking cessation.

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