Vitamins, minerals & supplements Archive

For these popular pills, the evidence has been mixed. Here's advice about getting the recommended amounts of both nutrients.

In the body, calcium and vitamin D work together to build and maintain healthy bones. Many adults (especially women) take these two nutrients in supplement form, hoping to stave off osteoporosis, the bone-weakening disease that leaves older people prone to fractures. But how do these supplements affect cardiovascular health?

The answer is a bit complicated. Here are the key points, with additional context and advice below:

Taking these medications at bedtime rather than in the morning may make them more effective.

Many people take their medications as part of their morning ritual, along with a cup of coffee and the daily newspaper. But for blood pressure drugs, evening may be a better option. Last year, a large study found that taking blood pressure drugs before bed may lower the risk of serious heart-related complications more than taking the drugs in the morning (see "Benefits of bedtime blood pressure dosing").

The concept of chronotherapy, or adjusting medication dosing to a specific time of day, isn't new. There's not a great deal of evidence to support the practice with cardiovascular drugs, but it makes sense, says Dr. Naomi Fisher, director of the Hypertension Specialty Clinic at Harvard-affiliated Brigham and Women's Hospital.

Careful planning may help you avoid side effects.

It's always concerning when the doctor says you need a procedure that requires anesthesia. On top of worries about the procedure itself, you may wonder how you'll react to anesthesia, especially now that you're older. The answer is complicated.

Aging changes everyone's basic physiology. Anesthesia introduces some risk, but less so than the risk from underlying health conditions, the surgical procedure itself, and the care you receive after surgery," says Dr. Angela Bader, an anesthesiologist and founding director of the Weiner Center for Preoperative Evaluation at Harvard-affiliated Brigham and Women's Hospital.

News briefs

Nuts are rich in healthy fat and calories, so you may not think of them as tools for weight control. But nuts may actually help in the battle of the bulge, suggests a Harvard study published online Sept. 23, 2019, by BMJ Nutrition, Prevention, and Health. Researchers analyzed questionnaire responses on dietary habits, physical activity, and weight changes from about 145,000 middle-aged and older men and women. People who went from never eating nuts to eating a daily average of at least half a serving (about half a handful) were 16% less likely to become obese over a four-year period compared with people who didn't eat nuts at all. Substituting a half serving of nuts per day for red meat, processed meat, French fries, desserts, or potato chips was also associated with less weight gain. "Nuts have protein and fiber which help us feel full longer and offset cravings for junk food. Although nuts are high in calories, up to 20% of calories from nut consumption will be excreted from our body," says Dr. Xiaoran Liu, one of the study authors and a research associate with the Harvard T.H. Chan School of Public Health.

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Researchers examining dietary data from over 50,000 postmenopausal women found that women who ate foods with a higher glycemic index, and foods with more added sugars, were more likely to have insomnia.

Eating more unprocessed, plant-based foods is one of the best ways you can protect your heart.

What do you usually eat for breakfast? How about for lunch and dinner? These questions are standard fare during a consultation with Dr. Ron Blankstein, a preventive cardiologist at Harvard-affiliated Brigham and Women's Hospital. The answers help him tailor the dietary advice he gives, which can have a profound effect on the future health of his patients' hearts.

"Most people really aren't aware of the importance of a healthy diet, or they're confused about what they should be eating," says Dr. Blankstein. About five years ago, he revamped his own diet to follow what the current evidence suggests is the best way to avoid heart disease: a whole-food, plant-based style of eating. "I find that when I tell my patients I follow this diet myself, they're far more likely to buy into it," he says. (For an idea of what he typically eats, see "A day of plant-based meals.")

Ask the doctor

Q. Just before the holidays, I heard that a study said it was okay to eat red meat. Previously, you've said just the opposite. Help!

A. We got lots of letters like yours. The bottom line is that we stick by our longstanding advice: avoid frequent meals of red meat, and especially processed meat.